Categorie
Oxaloplatine [French]
Les marques,
Oxaloplatine [French]
Analogs
Oxaloplatine [French]
Les marques melange
No information avaliable
Oxaloplatine [French]
Formule chimique
C8H12N2O4Pt
Oxaloplatine [French]
RX lien
http://www.rxlist.com/cgi/generic/eloxatin.htm
Oxaloplatine [French]
FDA fiche
Oxaloplatine [French]
msds (fiche de securite des materiaux)
Oxaloplatine [French]
Synthese de reference
Aucune information disponible
Oxaloplatine [French]
Poids moleculaire
395.27 g/mol
Oxaloplatine [French]
Point de fusion
No information avaliable
Oxaloplatine [French]
H2O Solubilite
Aucune information disponible
Oxaloplatine [French]
Etat
Solid
Oxaloplatine [French]
LogP
No information avaliable
Oxaloplatine [French]
Formes pharmaceutiques
Aucune information disponible
Oxaloplatine [French]
Indication
Pour le traitement des tumeurs malignes du côlon, du rectum, et de l'ovaire
Oxaloplatine [French]
Pharmacologie
L'oxaliplatine inhibe sélectivement la synthèse de l'acide désoxyribonucléique (ADN). Le contenu guanine et la cytosine est corrélée avec le degré d'oxaliplatine induit une réticulation. A des concentrations élevées de la drogue, de l'ARN cellulaire et la synthèse des protéines sont également supprimées.
Oxaloplatine [French]
Absorption
Aucune information disponible
Oxaloplatine [French]
Toxicite
Aucune information disponible
Oxaloplatine [French]
Information pour les patients
Patients and patientsí caregivers should be informed of the expected side effects of ELOXATIN, particularly
its neurologic effects, both the acute, reversible effects, and the persistent neurosensory toxicity. Patients should
be informed that the acute neurosensory toxicity may be precipitated or exacerbated by exposure to cold or cold
objects. Patients should be instructed to avoid cold drinks, use of ice, and should cover exposed skin prior to
exposure to cold temperature or cold objects.
Patients must be adequately informed of the risk of low blood cell counts and instructed to contact their
physician immediately should fever, particularly if associated with persistent diarrhea, or evidence of infection
develop.
Patients should be instructed to contact their physician if persistent vomiting, diarrhea, signs of dehydration,
cough or breathing difficulties occur, or signs of allergic reaction appear.
Oxaloplatine [French]
Organismes affectes
Les humains et autres mammifères